Moss Nutrition Digest: Acacia Fiber: Benefits Beyond Your Gut
By Diana Allen, MS, CNS, Product Development Manager
02/15/2019 - Moss Nutrition Digest #9
Acacia Fiber: Benefits Beyond the Gut
Acacia fiber, also
known as gum arabic, is a soluble fiber made from the dried sap of the acacia
tree. The fiber functions as a prebiotic and is commonly used to support
gastrointestinal health. People with GI issues such as IBS often take acacia
fiber to help improve digestive ease and comfort, support gut lining repair,
promote regularity and add firmness to the stool.
fibers such as acacia also may offer benefits beyond the GI tract, and can be
useful in helping modulate a healthy inflammation response elsewhere in the
When soluble fiber enters the large
intestine, it is fermented by microbes that produce butyrate, an essential
four-carbon fatty acid, as a by-product. Butyrate, the primary fuel of colonic enterocytes,
also exhibits potent anti-inflammatory effects. In colitis patients, for
example, butyrate has been shown to reduce levels of the inflammatory cytokine
TNF-alpha, via mechanisms such as inhibiting NF-kappa B. But what about people
with other types of inflammatory disorders?
A 12-week Phase II Clinical trial
published in 2018 studied 40 rheumatoid arthritis patients between the ages of
18 and 70, mostly female with a mean age of 55. All subjects were instructed to
consume 30 grams of acacia fiber, dissolved in water, once per day in the
morning, and to keep track of their symptoms.
Measurements of each participant's serum
levels of TNF-alpha (an inflammatory cytokine) and the inflammatory marker ESR
were taken at baseline and throughout the course of the trial, at 1 month
intervals. A disease activity score panel known as the DAS28-widely used as an
indicator to evaluate RA activity and treatment response-also was obtained following
the same schedule.
The remarkable results of this trial
found a significant reduction in inflammatory markers and improvement in
symptoms in all subjects. ESR levels decreased after one month and remained low
throughout the course of the study. TNF-alpha levels were also significantly
decreased, as were the number of tender and swollen joints per subjective
reporting and DAS28 scores.
Nutrition Acacia Fiber is a 100%
organic pure powder supplement that dissolves easily in cool water. By serving as a substrate for
colonic microbial fermentation, Acacia
Fiber can help increase butyrate production to beneficially modulate the
gut microbiome and promote healthy gut-associated immune function. Current
research further suggests acacia fiber may help to optimize the inflammation
response in extra-intestinal systems, an exciting new finding.
Full study access at: https://www.hindawi.com/journals/ijr/2018/4197537/